Bioinformatics Database
MIR665: microRNA 665
Cellular Process
Dentin formation
Gene Name
MIR665: microRNA 665
Gene ID
100126315
Gene Sequence
General Description
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs.The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA.
Alternative titles; symbols
Chromosome
Chromosome 14
Cytogenetic location
14q32.2
Encoded Protein
Function of the protein in oral and tooth development
The miRNA pathway is evident to have significant importance in embryogenesis including tooth development. miRNAs are found to regulate morphogenesis of tooth by fine-tuning the signalling networks. However, their precise role in tooth differentiation and morphogenesis is unclear (Khuu et al., 2016)
Dental and Oral Diseases
Protein Sequence
Mutations
Related Literature
Khuu et al., (2016): https://doi.org/10.2174/2211536605666160706003256
